1. How long do statins take to achieve their maximum benefit? 2. If, after 4 months of taking…

1. How long do statins take to achieve their maximum benefit? 2. If, after 4 months of taking simvastatin (20 mg daily), a patient with hyperlipidaemia and hypertension has an increased aspartate transferase (AST) of up to 60 U/L, with a normal alanine transferase (ALT), what action should I take? 3. How long should the statins be continued once the lipid profile returns to normal? Can we stop the statins once normal levels are attained and then continue with diet modification?

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