1. Should a patient poorly controlled on glibenclamide 15 mg a day and metformin 1500 mg a day be…

1. Should a patient poorly controlled on glibenclamide 15 mg a day and metformin 1500 mg a day be moved onto insulin? 2. What are the indications for insulin in type 2 diabetics? 3. What happens to the insulin-secreting capacity of a type 2 diabetic placed on insulin therapy earlier than recommended? Can the external supply of insulin improve the functional capacity of the insulin-secreting cells, to some extent by providing some rest to these cells?

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