1. What dose of Synacthen is equivalent to adrenocorticotrophic hormone (ACTH)? 2. I want to know…

1. What dose of Synacthen is equivalent to adrenocorticotrophic hormone (ACTH)? 2. I want to know the mechanism that causes anaemia in Addison’s disease. I am unable to find the real cause. 3. What causes hypercalcaemia in Addison’s disease? 4. In the diagnosis of Cushing’s disease using the high-dose dexamethasone suppression test, how can the exogenous steroid suppress adrenocorticotrophic hormone (ACTH) when the grossly elevated serum cortisol levels fail to do so?

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