1. Why is thyroid-stimulating hormone (TSH) normal or increased 6in patients with peripheral…

1. Why is thyroid-stimulating hormone (TSH) normal or increased 6in patients with peripheral resistance to tri-iodothyronine (T3) and thyroxine (T4)? The thyroid hormone levels are high in these patients, so the TSH should drop lower: why doesn’t it? 2. Thyroxine is a peptide hormone used to treat thyroid deficiency and other thyroid disorders. It is taken orally. Peptides are broken down into amino acids before being absorbed. What factors cause the thyroxine to remain stable in the digestive tract so that it is absorbed without being digested?

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