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Asthma

Jean just got home from her gardening class. She has noticed that every time she finishes her class, she keeps on coughing and coughing. She also feels that her chest tightens and she has trouble breathing. Today, she almost could not breathe that she hurriedly drove to the nearest emergency room. The ER physician diagnosed her with asthma.

Description


Asthma affects people in their different stages in life, yet it can be avoided and treated. asthma-pathophysiology
  • Asthma is a chronic inflammatory disease of the airways that causes airway hyperresponsiveness, mucosal edema, and mucus production.
  • Inflammation ultimately leads to recurrent episodes of asthma symptoms.
  • Patients with asthma may experience symptom-free periods alternating with acute exacerbations that last from minutes to hours or days.
  • Asthma, the most common chronic disease of childhood, can begin at any age.

Pathophysiology


The underlying pathophysiology in asthma is reversible and diffuse airway inflammation that leads to airway narrowing.
  • Activation. When the mast cells are activated, it releases several chemicals called mediators.
  • Perpetuation.These chemicals perpetuate the inflammatory response, causing increased blood flow, vasoconstriction,, fluid leak from the vasculature, attraction of white blood cells to the area, and bronchoconstriction.
  • Bronchoconstriction. Acute bronchoconstriction due to allergens results from a release of mediators from mast cells that directly contract the airway.
  • Progression. As asthma becomes more persistent, the inflammation progresses and other factors may be involved in the airflow limitation.
Schematic Diagram [scribd id=136228783 key=key-ba99bnqc7zmpz8kbzpx mode=scroll]

Statistics and Epidemiology


Asthma is considered as the most common chronic disease of childhood, and is a disruptive disease that affects school and work attendance.
  • Asthma affects more than 22 million people in the United States.
  • Asthma accounts for more than 497, 000 hospitalizations annually.
  • The total economic cost of asthma exceeds $27.6 billion.

Causes


Despite increased knowledge on the pathology of asthma and the development of improved medications and management plans, the death rate from the disease continues to rise. Here are some of the factors that influence the development of asthma.
  • Allergy. Allergy is the strongest predisposing factor for asthma.
  • Chronic exposure to airway irritants. Irritants can be seasonal (grass, tree, and weed pollens) or perennial (mold, dust, roaches, animal dander).
  • Exercise. Too much exercise can also cause asthma.
  • Stress/ Emotional upset. This can trigger constriction of the airway leading to asthma.
  • Medications. Certain medications can trigger asthma.

Clinical Manifestations


The signs and symptoms of asthma can be easily identified, so once the following symptoms are observed, a visit to the physician is necessary.
  • Most common symptoms of asthma are cough (with or without mucus production), dyspnea, and wheezing (first on expiration, then possibly during inspiration as well).
  • Cough. There are instances that cough is the only symptom.
  • Dyspnea. General tightness may occur which leads to dyspnea.
  • Wheezing. There may be wheezing, first on expiration, and then possibly during inspiration as well.
  • Asthma attacks frequently occur at night or in the early morning.
  • An asthma exacerbation is frequently preceded by increasing symptoms over days, but it may begin abruptly.
  • Expiration requires effort and becomes prolonged.
  • As exacerbation progresses, central cyanosis secondary to severe hypoxia may occur.
  • Additional symptoms, such as diaphoresis, tachycardia, and a widened pulse pressure, may occur.
  • Exercise-induced asthma: maximal symptoms during exercise, absence of nocturnal symptoms, and sometimes only a description of a “choking” sensation during exercise.
  • A severe, continuous reaction, status asthmaticus, may occur. It is life-threatening.
  • Eczema, rashes, and temporary edema are allergic reactions that may be noted with asthma.

Prevention


Patients with recurrent asthma should undergo tests to identify the substances that precipitate the symptoms.
  • Allergens. Allergens, either seasonal or perennial, can be prevented through avoiding contact with them whenever possible.
  • Knowledge. Knowledge is the key to quality asthma care.
  • Evaluation. Evaluation of impairment and risk are key in the control.

Complications


Complications for asthma include the following:
  • Status asthmaticus. Airway obstruction in status asthmaticus often results in hypoxemia.
  • Respiratory failure. Asthma, if left untreated, progresses to respiratory failure.
  • Pneumonia. Mucus that pools in the lungs and becomes infected can lead to the development of pneumonia.

Assessment and Diagnostic Findings


To determine the diagnosis of asthma, the clinician must determine that episodic symptoms of airway obstruction are present.
  • Positive family history. Asthma is a hereditary disease, and can be possibly acquired by any member of the family who has asthma within their clan.
  • Environmental factors. Seasonal changes, high pollen counts, mold, pet dander, climate changes, and air pollution are primarily associated with asthma.
  • Comorbid conditions. Comorbid conditions that may accompany asthma may include gastroeasophageal reflux, drug-induced asthma, and allergic broncopulmonary aspergillosis.

Medical Management


Immediate intervention may be necessary, because continuing and progressive dyspnea leads to increased anxiety, aggravating the situation.

Pharmacologic Therapy

  • Short-acting beta2adrenergic agonists. These are the medications of choice for relief of acute symptoms and prevention of exercise-induced asthma.
  • Anticholinergics. Anticholinergics inhibit muscarinic cholinergic receptors and reduce intrinsic vagal tone of the airway.
  • Corticosteroids. Corticosteroids are most effective in alleviating symptoms, improving airway function, and decreasing peak flow variability.
  • Leukotriene modifiers. Anti Leukotrienes are potent bronchoconstrictors that also dilate blood vessels and alter permeability.
  • Immunomodulators. Prevent binding of IgE to the high affinity receptors of basophils and mast cells.

Peak Flow Monitoring

Peak Flow Meter
Peak Flow Meter. Image via: medlineplus.gov
  • Peak flow meters. Peak flow meters measure the highest airflow during a forced expiration.
  • Daily peak flow monitoring. This is recommended for patients who meet one or more of the following criteria: have moderate or severe persistent asthma, have poor perception of changes in airflow or worsening symptoms, have unexplained response to environmental or occupational exposures, or at the discretion of the clinician or patient.
  • Function. If peak flow monitoring is used, it helps measure asthma severity and, when added to symptom monitoring, indicates the current degree of asthma control.

Nursing Management


The immediate care of patients with asthma depend on the severity of the symptoms.

Nursing Assessment

Assessment of a patient with asthma includes the following:
  • Assess the patient’s respiratory status by monitoring the severity of the symptoms.
  • Assess for breath sounds.
  • Assess the patient’s peak flow.
  • Assess the level of oxygen saturation through the pulse oximeter.
  • Monitor the patient’s vital signs.

Nursing Diagnosis

Based on the data gathered, the nursing diagnoses appropriate for the patient with asthma include:

Nursing Care Planning & Goals

Main Article: 5 Bronchial Asthma Nursing Care Plans

To achieve success in the treatment of a patient with asthma, the following goals should be applied:
  • Maintenance of airway patency.
  • Expectoration of secretions.
  • Demonstration of absence/reduction of congestion with breath sounds clear, respirations noiseless, improved oxygen exchange.
  • Verbalization of understanding of causes and therapeutic management regimen.
  • Demonstration of behaviors to improve or maintain clear airway.
  • Identification of potential complications and how to initiate appropriate preventive or corrective actions.

Nursing Interventions

The nurse generally performs the following interventions:
  • Assess history. Obtain a history of allergic reactions to medications before administering medications.
  • Assess respiratory status. Assess the patient’s respiratory status by monitoring the severity of symptoms, breath sounds, peak flow, pulse oximetry, and vital signs.
  • Assess medications. Identify medications that the patient is currently taking. Administer medications as prescribed and monitor the patient’s responses to those medications; medications may include an antibiotic if the patient has an underlying respiratory infection.
  • Pharmacologic therapy. Administer medications as prescribed and monitor patient’s responses to medications.
  • Fluid therapy. Administer fluids if the patient is dehydrated.

Evaluation

To determine the effectiveness of the plan of care, evaluation must be performed. The following must be evaluated:
  • Maintenance of airway patency.
  • Expectoration or clearance of secretions.
  • Absence /reduction of congestion with breath sound clear, noiseless respirations, and improved oxygen exchange.
  • Verbalized understanding of causes and therapeutic management regimen.
  • Demonstrated behaviors to improve or maintain clear airway.
  • Identified potential complications and how to initiate appropriate preventive or corrective actions.

Discharge and Home Care Guidelines

A major challenge is to implement basic asthma management principles at the home and community level.
  • Collaboration. The complex therapy of treating asthma at home needs collaboration between the patient and the health care provider to determine the desired outcomes and to formulate a plan to achieve those outcomes.
  • Health education. Patient teaching is a critical component of care for patients with asthma. Teach patient and family about asthma (chronic inflammatory), purpose and action of medications, triggers to avoid and how to do so, and proper inhalation technique. Instruct patient and family about peak-flow monitoring. Obtain current educational materials for the patient based on the patient’s diagnosis, causative factors, educational level, and cultural background.
  • Compliance to therapy. Nurses should emphasize adherence to the prescribed therapy, preventive measures, and the need to keep follow-up appointments with health care providers. Teach patient how to implement an action plan and how and when to seek assistance.
  • Home visits. Home visits by the nurse to assess the home environment for allergens may be indicated for patients with recurrent exacerbations.

Documentation Guidelines

Documentation is a necessary part of the nursing care provided, and the following data must be documented:
  • Related factors for individual client.
  • Breath sounds, presence and character of secretions, and use of accessory muscles for breathing.
  • Character of cough and sputum.
  • Respiratory rate, pulse oximetry/o2 saturation, and vital signs.
  • Plan of care and who is involved in planning.
  • Teaching plan.
  • Client’s response to interventions, teaching, and actions performed.
  • Use of respiratory devices/airway adjuncts.
  • Response to medications administered.
  • Attainment or progress towards desired outcomes.
  • Modifications to the plan of care.

Practice Quiz: Asthma


Let’s reinforce what you’ve learned with this 5-item NCLEX practice quiz about Asthma.

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In Exam Mode: All questions are shown but the results, answers, and rationales (if any) will only be given after you’ve finished the quiz.

Practice Quiz: Asthma

Congratulations - you have completed Practice Quiz: Asthma. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rated as %%RATING%%
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Practice Mode: This is an interactive version of the Text Mode. All questions are given in a single page and correct answers, rationales or explanations (if any) are immediately shown after you have selected an answer. No time limit for this exam.

Practice Quiz: Asthma

Congratulations - you have completed Practice Quiz: Asthma. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rated as %%RATING%%
Your answers are highlighted below.

Text Mode

Text Mode: All questions and answers are given on a single page for reading and answering at your own pace. Be sure to grab a pen and paper to write down your answers. 1. Histamine, a mediator that supports the inflammatory process in asthma, is secreted by: A. Eosinophils B. Lymphocytes C. Mast cells D. Neutrophils 2. Obstruction of the airway in the patient with asthma is caused by all of the following except: A. Thick mucus B. Swelling of bronchial membranes C. Destruction of the alveolar wall D. Contraction of muscles surrounding the bronchi 3. A commonly prescribed mast cell stabilizer used for asthma is: A. Albuterol B. Budesonide C. Cromolyn sodium D. Theophylline 4. There are several comorbid conditions that accompany asthma but it does not include: A. Gastroeasophageal reflux B. Drug-induced asthma C. Hypertension D. Allergic bronchopulmonary aspergillosis 5. The strongest predisposing factor for asthma is: A. Chronic exposure to airway irritants B. Exercise C. Medications D. Allergy Answers and Rationale 1. Answer: C. Mast cells
  • C: When the mast cells are activated, it releases several chemicals called mediators, and one of them is histamine.
  • A: Eosinophils are part of the inflammatory process in asthma.
  • B: Lymphocytes have a role in the inflammatory process in asthma.
  • D: Neutrophils are part of the inflammatory process in asthma.
2. Answer: C. Destruction of the alveolar wall
  • C: There is no destruction of the alveolar wall in asthma.
  • A: Thick mucus causes obstruction of the airway.
  • B: Swelling of the bronchial membranes causes bronchoconstriction or obstruction of the airway.
  • D: Contraction of muscles surrounding the bronchi is a cause of obstruction of the airway.
3. Answer: C. Cromolyn sodium
  • C: Cromolyn sodium is a mast stabilizer commonly prescribed for patients with asthma.
  • A: Albuterol is not a mast cell stabilizer; it is a short-acting beta2 adrenergic agonist.
  • B: Budesonide is an inhaled corticosteroid.
  • D: Theophylline is classified as methylxanthine.
4. Answer: C. Hypertension
  • C: Hypertension is not a comorbid condition of asthma.
  • A: GERD occurs along with asthma in some patients.
  • B: Drug-induced asthma is a comorbid condition of asthma.
  • D: Allergic bronchopulmonary aspergillosis is a comorbid condition of asthma.
5. Answer: D. Allergy
  • D: Allergy is the strongest predisposing factor for asthma.
  • A: One of the causes of chronic exposure to airway irritants.
  • B: Exercise is one of the predisposing factors of asthma.
  • C: Medications can also start the development of asthma.

See Also


Posts related to Asthma:

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