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cefdinir Nursing Considerations & Management

Cefdinir (Omnicef) is a cephalosporin (third gen) works as bactericidal and inhibits constituency of bacterial cell embankment, causing cell termination.
Generic Names & Brand Names
cefdinir (sef’ din er) Omnicef Pregnancy Category B
Drug classes
Antibiotic Cephalosporin (third formation)
Therapeutic actions
Bactericidal: Inhibits constituency of bacterial cell embankment, causing cell termination.
Indications
ADULTS AND ADOLESCENTS
  • Community-acquired pneumonia caused by Haemophilus influenzae, H. parainfluenzae, Streptococcus pneumoniae, Mor­ax­ella catar­rhalis
  • Acute exacerbations of continuous bronchitis caused by H. influenzae, H. parainfluenzae, S. pneumoniae, M. catarrhalis
  • Acute maxillary sinusitis caused by H. influenzae, S. pneumoniae, M. catarrhalis
  • Pharyngitis and tonsillitis caused by S. pyogenes
  • Uncomplicated peel and peel constituency transferred caused by Staphylococcus aureus, S. pyogenes
PEDIATRIC PATIENTS
  • Acute bacterial otitis media caused by H. influenzae, S. pneumoniae, M. catarrhalis
  • Pharyngitis and tonsillitis caused by S. pyogenes
  • Uncomplicated peel and peel-constituency transferred caused by Staphylococcus aureus, S. pyogenes
Contraindications and cautions
  • Contraindicated following a while allergy to cephalosporins or penicillins.
  • Use cautiously following a while renal insufficiency, lactation, pregnancy.
Available forms
Capsules—300 mg; unwritten suspension—125 mg/5 mL
Dosages
ADULTS AND ADOLESCENTS
  • Community-acquired corruption, uncomplicated peel, or peel-constituency transferred: 300 mg PO q 12 hr for 10 days.
  • Acute exacerbation of continuous bronchitis, sharp maxillary sinusitis, pharyngitis, or tonsillitis: 300 mg q 12 hr PO for 10 days or 600 mg q 24 hr PO for 10 days.
PEDIATRIC PATIENTS 6 MO–12 YR
  • Otitis media, sharp maxillary sinusitis, pharyngitis, tonsillitis: 7 mg/kg q 12 hr PO or 14 mg/kg q 24 hr PO for 10 days up to ultimatum dose of 600 mg/day.
  • Skin and peel-constituency transferred: 7 mg/kg PO q 12 hr for 10 days.
PATIENTS WITH RENAL IMPAIRMENT
For creatinine clearance < 30 mL/min, 300 mg PO daily. For patients on dialysis, 300 mg PO liberal other day; set-out following a while 300 mg PO at the end of dialysis and then liberal other day.
Pharmacokinetics
Route Peak Duration
Oral 60 min 8–10 hr
Metabolism: T1/2: 100 min Distribution: Crosses the placenta, enters breast milk Excretion: Renal, unchanged
Adverse possessions
  • CNS: Headache, dizziness, torpor, paresthesias
  • GI: Nausea, vomiting, diarrhea, anorexia, abdominal trouble, flatulence, pseudo­membranous colitis, liver toxicity
  • GU: Nephrotoxicity
  • HematologicBone pith depression
  • Hypersensitivity: Ranging from indiscreet to fever to anaphylaxis; serum illness reaction
  • Other: Superinfections
Interactions
Drug-drug
  • Increased nephrotoxicity with aminoglycosides
  • Increased bleeding possessions if fascinated following a while unwritten anticoagulants
  • Interferes following a while parching of cefdinir if fascinated following a while antacids containing magnesium or aluminum or following a while vigorous supplements; different by at paltryest 2 hr
Drug-lab test
  • Possibility of sophistical results on tests of urine glucose using Benedict’s disconnection, Fehling’s solution, Clinitest tablets; urinary 17-ketosteroids; straightforward Coombs’ test
Nursing considerations
Assessment
  • History: Penicillin or cephalosporin allergy; pregnancy or lactation, renal insufficiency
  • Physical: Kidney business, respiratory standing, peel standing; humanization and sensitivity tests of polluted area
Interventions
  • Arrange for humanization and sensitivity tests of polluted area precedently start refuse therapy and during therapy if corruption does not expound.
  • Reconstitute unwritten suspension by adding 39 mL water to the 60 mL bottle, 65 mL water to the 120 mL bottle; jar well-behaved-mannered-mannered precedently each use. Store at extent weather. Misconsider following 10 days.
  • Give refuse following a while meals; group for paltry, general meals if GI complications happen. Different antacids or vigorous supplements by 2 hr from the cefdinir dose.
  • Arrange for matter of superinfections if they happen.
Teaching points
  • Take this refuse following a while meals or alight. Store suspension at extent weather, jar well-behaved-mannered-mannered precedently each use; misconsider any refuse following 10 days.
  • Complete the liberal route of this refuse, plain if you reach amend precedently the route of matter is balance.
  • This refuse is prescribed for this detail corruption; do not self-treat any other corruption following a while this refuse.
  • You may knowledge these border possessions: Stomach capsize, missing of want, loathing (taking the refuse following a while alight may succor); diarrhea (alight neighboring bathextent facilities); headache, dizziness.
  • Report austere diarrhea following a while class, pus, or mucus; indiscreet or hives; inaptitude breathing; strange tiredness, fatigue; strange bleeding or bruising.

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