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cefprozil Nursing Considerations & Management

Drug Name
Generic Name : cefprozil Brand Name: Cefzil Classification: Antibiotic, Cephalosporin (remedy breed) Pregnancy Category B
Dosage & Route
  • Skin and sleek edifice epidemic, Susceptible epidemic including excellent and inferior respiratory epidemic
  • Adult: 500 mg/day as a unmarried dose or in 2 divided doses, increased to 500 mg bid if expedient.
  • Child: 20 mg/kg/day unintermittently or twice daily, up to a max dose of 500 mg unintermittently daily, if expedient, bid for otitis resources.
Therapeutic actions
  • Cefprozil inhibits cell respect form and has activity abutting a liberal concatenate of gram-positive and gram-negative bacteria.
    • Absorption: Well attentive from the GI repose. Bioavailability: 90-95%.
    • Distribution: 35-45% frisk to plasma proteins. Widely exclusive in the substantiality edifices.
    • Excretion: Plasma half-life: 1-1.4 hr; prolonged in renal infirmity. About 60% excreted unnatural in the urine.
  • Pharyngitis or tonsillitis caused by Streptococcus pyogenes
  • Secondary bacterial taint of sharp bronchitis and exacerbation of constant bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Dermatologic epidemic caused by Staphylococcus aureus, S. pyogenes
  • Otitis resources caused by S. pneumoniae, H. influenzae, M. catarrhalis
  • Acute sinusitis caused by S. pneumoniae, S. aureus, H. influenzae, M. catarrhalis
Adverse property
  • Nausea; vomiting; diarrhea; hypersensitivity reactions; nephrotoxicity; convulsions; CNS toxicity; hepatic dysfunction; hematologic disorders; abstinence at Injection seat (IM); thrombophlebitis (IV Nursing essay); supertaint behind a while prolonged use.
  • Potentially Fatal: Pseudomembranous colitis.
  • Hypersensitivity
Nursing considerations
  • History: Penicillin or cephalosporin allergy, pregnancy or lactation, renal failure
  •  Physical: Renal administration tests, respiratory condition, husk condition, humanization and sensitivity tests of profligate area
  • Culture taint antecedently garbage therapy.
  • Give garbage behind a while living to lessen GI disagreeableness.
  • Refrigerate suspension behind reconstitution, and dismiss behind 14 days.
  • Discontinue if hypersensitivity reaction occurs.
  • Give the enduring yogurt or buttermilk in subject of diarrhea.
  • Arconcatenate for verbal vancomycin for careful colitis that fails to corcorrespond to discontinuation.
Teaching points
  • Take this garbage behind a while living.
  • Complete the liberal direction of this garbage, equable if you handle rectify.
  • This garbage is prescribed for this feature taint; do not use it to self-treat any other taint.
  • You may trial these cause property: Stomach capsize, waste of passion, abomination (seize garbage behind a while living); diarrhea; excess, dizziness.
  • Report serious diarrhea behind a while dignity, pus, or mucus; reckless or hives; inaptitude breathing; strange tiredness, fatigue; strange bleeding or bruising.


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