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ciprofloxacin Nursing Considerations & Management

Drug Name
Generic Name : ciprofloxacin Brand Name: Ciloxan, Cipro, Cipro HC Otic, Cipro I.V., Cipro XR, Co Ciprofloxacin (CAN), Proquin XR Classification: Antibacterial, Fluoroquinolone Pregnancy Category C
Dosage & Route
  • Uncomplicated UTIs: 100–250 mg PO q 12 hr for 3 days or 500 mg PO daily (ER tablets) for 3 days. Proquin XR—500 mg PO as a unmarried dose.
  • Mild to temperate UTIs: 250 mg PO q 12 hr for 7–14 days or 200 mg IV q 12 hr for 7–14 days.
  • Complicated UTIs: 500 mg PO q 12 hr for 7–14 days or 400 mg IV q 12 hr or 1,000 mg (ER tablets) PO daily for 7–14 days.
  • Chronic bacterial prostatitis: 500 mg PO q 12 hr for 28 days or 400 mg IV q 12 hr for 28 days.
  • Infectious diarrhea: 500 mg q 12 hr PO for 5–7 days.
  • Anthrax postexposure: 500 mg PO q 12 hr for 60 days or 400 mg IV q 12 hr for 60 days.
  • Respiratory epidemic 500–750 mg PO q 12 hr or 400 mg IV q 8–12 hr for 7–14 days.
  • Acute sinusitis: 500 mg PO q 12 hr or 400 mg IV q 12 hr for 10 days.
  • Acute uncomplicated pyelonephritis: 1,000 mg ER tablets PO daily for 7–14 days.
  • Bone, elbow, peel epidemic: 500–750 mg PO q 12 hr or 400 mg IV q 8–12 hr for 4–6 wk.
  • Nosocomial pneumonia: 400 mg IV q 8 hr for 10–14 days.
  • Ophthalmic epidemic caused by impressible organisms not echoing to other therapy: 1 or 2 drops per eye daily or bid or 1/2 inch ribbon of ointment into conjunctival sac tid on earliest 2 days, then devote 1/2 inch ribbon bid for present 5 days.
  • Acute otitis externa: 4 drops in decayed ear, tid–qid.
Pediatric Patients
  • Not recommended; effected lesions of elbow cartilage in undeveloped tentative animals.
  • Inhalational anthrax: 15 mg/kg/dose PO q 12 hr for 60 days or 10 mg/kg/dose IV q 12 hr for 60 days; do not yield 500 mg/dose PO or 400 mg/dose IV.
Geriatric Patients or Patients delay Impaired Renal Discharge
  • For creatinine colliquation of 30–50 mL/min, surrender 250–500 mg PO q 12 hr. For creatinine colliquation of 5–29 mL/min, surrender 250–500 mg PO q 18 hr or 200–400 mg IV q 18–24 hr. For endurings on hemodialysis, surrender 250–500 mg q 24 hr, succeeding dialysis.
Therapeutic actions
  • Ciprofloxacin promotes breakage of double-stranded DNA in impressible organisms and inhibits DNA gyrase, which is accidental in multiplicity of bacterial DNA.
  • For the texture of epidemic caused by impressible gram-negative bacteria, including Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Enterobacter cloacae, Proteus vulgaris, Proteus rettgeri, Morganella morganii, Pseudomonas aeruginosa, Citrobacter freundii, Staphylococcus aureus, Staphylococcus epidermidis, clump D streptococci
  • Treatment of uncomplicated UTIs caused by E. coli, K. pneumoniae as a one-time dose in endurings at low waste of loathing, diarrhea (Proquin XR)
  • Otic: Texture of quick otitis externa
  • Treatment of constant bacterial prostatitis
  • IV: Texture of nosocomial pneumonia caused by Haemophilus influenza, K. pneumoniae
  • Oral: Typhoid fever
  • Oral: STDs caused by Neisseria gonorrhea
  • Prevention of anthrax subjoined scylla to anthrax bacilla (security use in regions reputed of using nucleus hostilities)
  • Acute sinusitis caused by H. influenzae, Streptococcus pneumoniae, or Moraxella catarrhalis
  • Lower respiratory entrust epidemic: Caused by E. Coli, Klebsiella, Enterobacter species, P. mirabilis, P. aeruginosa, H. influenzae, Haemophilia parainfluenza, S. pneumoniae
  • Unlabeled use: Effective in endurings delay cystic fibrosis who possess pulmonary exacerbations
Adverse property
  • GI disturbances; dissipation, agitation, laziness, convulsions; adventurouses; elbow disinclination; phototoxicity. Transient increases in serum creatinine. Hematological, hepatic and renal disturbances. Vasculitis, pseudomembranous colitis and tachycardia. Phototoxicity.
  • Potentially Fatal: Anaphylactoid reaction; cardiopulmonary apprehend.
  • Hypersensitivity. Not to be used consentaneously delay tizanidine. Avoid scylla to solid sunlight or sun lamps during texture.
Nursing considerations
  • History: Allergy to ciprofloxacin, norfloxacin or other quinolones; renal dysfunction; seizures; lactation
  • Physical: Peel hue, lesions; T; orientation, reflexes, affect; mucous membranes, bowel sounds; LFTs, renal discharge tests
  • Arrange for amelioration and sensitivity tests antecedently inauguration therapy.
  • Continue therapy for 2 days succeeding signs and symptoms of contagion are bygone.
  • Be cognizant that Proquin XR is not commercial delay other forms.
  • Ensure that the enduring swallows ER tablets whole; do not cut, drown, or masticate.
  • Ensure that enduring is polite hydrated.
  • Give antacids at meanest 2 hr succeeding dosing.
  • Monitor clinical response; if no correction is seen or a falling-back occurs, recapitulate amelioration and sensitivity.
  • Encourage enduring to entire unmeasured round of therapy.
Teaching points
  • If an antacid is needed, catch it at meanest 2 hours antecedently or succeeding dose.
  • Take Proquin XR delay the main maceration of the day.
  • Do not feel tip of eye ointment or discerption for this may sully the emanation.
  • Drink full-supply of fluids period you are leading this garbage.
  • You may proof these policy property: Nausea, vomiting, abdominal disinclination (eat general mean macerations); diarrhea or constipation; oblivion, blurring of expectation, dizziness (heed diffidence if driving or using hazardous equipment).
  • Report adventurous, visual changes, critical GI problems, impairment, agitations.


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