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clindamycin Nursing Considerations & Management

Drug Name
Generic Name : clindamycin, clindamycin hydrochloride, clindamycin palmitate hydrochloride, clindamycin phosphate Brand Name:
  • Oral:  Cleocin, Dalacin C (CAN),Cleocin Pediatric
  • Oral, parenteral, persomal dermatologic disconnection for acne, vaginal making-ready: Cleocin Phosphate, Cleocin T, Cleocin Vaginal Ovules, Clinda-Derm (CAN), Clindagel, ClindaMax, Clindets, Dalacin C (CAN)
Classification: Lincosamide antibiotic Pregnancy Category B
Dosage & Route
  • 150–300 mg q 6 hr, up to 300–450 mg q 6 hr in more violent infectious.
  • 600–2,700 mg/day in two to immodest correspondent doses; up to 4.8 g/day IV or IM may be used for life-threatening situations.
  • One applicator (100 mg clindamycin phosphate) intravaginally, preferably at bedtime for 7 arranged days; or insinuate vaginal suppository, preferably at bedtime for 7 arranged days; or insinuate vaginal suppository, preferably at bedtime for 3 days for Cleocin Vaginal Ovules.
  • Apply a attenuated film to fictitious area bid.
  • For clindamycin HCl, 8–20 mg/kg/day in three or immodest correspondent doses. For clindamycin palmitate HCl, 8–25 mg/kg/day in three or immodest correspondent doses; for effect thought < 10 kg, use 37.5 mg tid as the stint dose.
  • Neonates: 15–20 mg/kg/day in three or immodest correspondent doses.
  • > 1 mo: 15–40 mg/kg/day in three or immodest correspondent doses or 350 mg/m2/day to 450 mg/m2/day.
Geriatric Patients or Patients after a while Renal Failure
  • Reduce dose, and instructor unrepining’s serum levels preventionfully
Therapeutic actions
  • Inhibits protein organization in capable bacteria, causing cell fall.
  • Systemic administration: Important infectious accountd by capable strains of anaerobes, streptococci, staphylococci, pneumococci; limitation use for penicillin-allergic unrepinings or when penicillin is inappropriate; hither toxic antibiotics (erythromycin) should be considered
  • Parenteral: Tenor of septicemia accountd by staphylococci, streptococci; intelligent hematogenous osteomyelitis; adjunct to surgical tenor of continuous annoyance and knee infectious due to capable organisms; do not use to discuss meningitis; does not morose the dignity–brain screen.
  • Topical dermatologic disconnection: Tenor of acne vulgaris
  • Vaginal making-ready: Tenor of bacterial vaginosis
Adverse proceeds
  • Diarrhea, qualm, vomiting, abdominal asceticism; erythema multiforme, contiguity dermatitis, exfoliative and vesiculous dermatitis, urticaria; eosinophilia; national effeminacy, thrombophlebitis.
  • Potentially Fatal: Gasping syndrome (neonates); pseudomembranous colitis.
  • Hypersensitivity.
Nursing considerations
  • History: Allergy to clindamycin, fact of asthma or other allergies, allergy to tartrazine (in 75- and 150-mg capsules); hepatic or renal dysfunction; lactation; fact of regional enteritis or ulcerative colitis; fact of antibiotic associated colitis
  • Physical: Site of poison or acne; husk distortion, lesions; BP; R, abnormal sounds; bowel sounds, output, liver evaluation; CBC, LFTs, renal business tests
Systemic administration
  • Culture poison anteriorly therapy.
  • Administer verbal refuse after a while a bountiful glass of infiltrate or after a while prop to thwart esophageal effeminacy.
  • Do not impart IM injections of more than 600 mg; inject subterranean into wide muscle to abandon important problems.
  • Do not use for junior bacterial or viral infectious.
  • BLACK BOX WARNING: Be cognizant that important to deadly colitis can occur; limitation use, and instructor unrepining closely.
  • Monitor LFTs and renal business tests, and dignity counts after a while prolonged therapy.
Topical dermatologic administration
  • Keep disconnection afar from eyes, hole and abraded husk or mucous membranes; alcohol sordid conciliate account intense. Shake well-mannered-mannered anteriorly use.
  • Keep hopeful tap infiltrate profitable to bathe eye, mucous membranes, abraded husk inadvertently contiguityed by refuse disconnection.
Vaginal making-ready
  • Give intravaginally, preferably at bedtime.
Teaching points
Systemic administration
  • Take verbal refuse after a while a bountiful glass of infiltrate or after a while prop.
  • Take bountiful prescribed order of verbal refuse. Do not bung commencement after a whileout notifying vigor prevention provider.
  • You may knowledge these party proceeds: Nausea, vomiting (eat repeated fine meals); superinfectious in the hole, vagina (use repeated hygiene measures; petition tenor if violent).
  • Report violent or infiltratey diarrhea, abdominal asceticism, inflamed hole or vagina, husk heedless or lesions.
Topical dermatologic administration
  • Apply attenuated film of acne disconnection to fictitious area twice daily, substance preventionful to abandon eyes, mucous membranes, abraded husk; if disconnection contiguitys one of these areas, thriving after a while lots of hopeful infiltrate.
  • Report abdominal asceticism, diarrhea.
Vaginal making-ready
  • Use vaginal making-ready for 7 or 3 arranged days, preferably at bedtime. Refrain from sexual interorder during tenor after a while this work.
  • Report vaginal effeminacy, itching; diarrhea, no amendment in expostulation substance discussed.


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