# Drug Dosage Calculations NCLEX Exam 2

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1. Doctor’s order: Amoxicillin 0.25 g p.o. every 8 hours; Available: Amoxicillin 125 mg tablets. How many tablets will the nurse give per dose?

1. 0.5 tab
2. 1 tab
3. 1.5 tabs
4. 2 tabs

2. Doctor’s order: Zofran 8 mg p.o. t.i.d.; Available: Zofran in a 100 ml bottle labeled 4 mg/tsp.; How many ml will the nurse administer for each dose?

1. 1.25 ml
2. 6.25 ml
3. 8 ml
4. 10 ml

3. Doctor’s order: Morphine gr 1/10; Available: Morphine 10 mg/ml. How many ml will the nurse give?

1. 0.6 ml
2. 1 ml
3. 6 ml
4. 10 ml

4. Give Fortaz mg/kg/day p.o. 50 mg/kg p.o. t.i.d. to a child who weighs 25.5 kg. Fortaz is available in an oral suspension labeled 100 mg/ml. How many ml would the nurse administer per dose?

1. 0.5 ml
2. 0. 8 ml
3. 10.8 ml
4. 12.8 ml

5. Give Ceclor 45 mg/kg/day p.o. in 3 divided doses for a patient who weighs 66 pounds. A 75 ml stock medication is labeled Ceclor 125 mg/ml. How many ml would the nurse administer per dose?

1. 0.5 ml
2. 0.8 ml
3. 3.6 ml
4. 9 ml

6. Give Biaxin for a child whose BSA is 0.55 m2. The usual adult dose is 500 mg. Biaxin is available in an oral suspension. The 100ml bottle is labeled 50 mg/ml. How many ml would the nurse give per dose?

1. 3.2 ml
2. 1.6 ml
3. 1.2 ml
4. 5 ml

7. Give Phenergan for a child whose BSA is 1.2 m2. The usual adult dose is 25 mg. How many milligrams would the nurse administer for the dose?

1. 12 mg
2. 17.6 mg
3. 20.8 mg
4. 25 mg

8. LR 125 ml/hr via gravity flow using tubing calibrated at 15 gtt/ml. Calculate the flow rate.

1. 8 gtt/min
2. 15 gtt/min
3. 25 gtt/min
4. 31 gtt/min

9. One liter NS to infuse over 24 hours using a micro drip (gravity flow). Calculate the flow rate.

1. 42 gtt/min
2. 28 gtt/min
3. 12 gtt/min
4. 10 gtt/min

10. At the change of shift you notice 200 ml left to count in the I.V. bag. The I.V. is infusing at 80 ml/hr. How much longer will the I.V. run?

1. 1 hr
2. 1 hr and 30 mins
3. 2 hrs
4. 2 hrs and 30 mins

11. Keflin 2 g in 100 ml D5W IVPB over 20 minutes. The I.V. tubing is 15 gtt/ml. Calculate the flow rate.

1. 150 gtt/min
2. 100 gtt/min
3.  75 gtt/min
4. 76 gtt/min

12. The physician writes an order for Heparin 900 units/hour. The label on the I.V. bag reads: Heparin 10,000 units in 500 ml D5W. How many ml/hr will deliver the correct dose?

1. 11 ml/hr
2. 45 ml/hr
3. 50 ml/hr
4.  55 ml/hr

13. Administer Heparin 1,000 units/hr from an I.V. bag mixed 40,000 units in 1 L D5W. How many ml/hr will deliver the correct amount of Heparin?

1. 40 ml/hr
2. 30 ml/hr
3. 25 ml/hr
4. 15 ml/hr

14. The patient’s Heparin is infusing at 28 ml/hr on an infusion pump. The bag of fluid is mixed 20,000 units of Heparin in 500 ml D5W. What hourly dose of heparin is the patient receiving?

1. 1,120 units/hr
2. 1,210 units/hr
3. 2,120 units/hr
4. 2,210 units/hr

15. The patient’s heparin drip is infusing at 11 ml/hr on an infusion pump. The bag of fluid is mixed 25,000 units of Heparin in 250 ml D5W. What hourly dose of Heparin is the patient receiving?

1. 2,500 units/hr
2. 2,000 units/hr
3. 1,000 units/hr
4. 1,100 units/hr

16. Give Regular insulin by continuous I.V. infusion at 20 units/hr. The solution is 250 ml NS with 100 units of Regular insulin. What rate on the infusion pump will deliver the correct dose?

1. 5 ml/hr
2. 8 ml/hr
3. 50 ml/hr
4. 100 ml/hr

17. Administer a Theophylline drip at 40 mg/hr The solution is 250 ml D5W + Theophylline 500 mg. What rate on the infusion pump will deliver the correct dose?

1. 20 ml/hr
2. 40 ml/hr
3. 80 ml/hr
4. 100 ml/hr

18. Give Tridil 15 mcg/min. Tridil is mixed 50 mg in 500 ml D5W. What rate on the infusion pump will deliver the correct dose?

1. 150 ml/hr
2. 15 ml/hr
3. 90 ml/hr
4. 9 ml/hr

19. Give propofol 10 mcg/kg/minute. The infusion is mixed propofol 250 mg in 250 ml D5W. The patient weighs 168 pounds. What rate on the infusion pump will deliver the correct dose?

1. 10 ml/hr
2. 26 ml/hr
3. 46 ml/hr
4. 50 ml/hr

20. Give Nitroprusside 5 mcg/kg/minute via continuous infusion for a patient weighing 205 lbs. Nitroprusside is available in a solution of 200 mg in 250 ml D5W. What rate on the infusion pump will deliver the correct dose?

1. 25 ml/hr
2. 35 ml/hr
3. 45 ml/hr
4. 50 ml/hr

21. Tridil is infusing at 15 ml/hr on an infusion pump. The drug is mixed 50 mg in 500 ml D5W. How many mcg/minute is the patient receiving?

1. 25 mcg/min
2. 35 mcg/min
3. 45 mcg/min
4. 50 mcg/min

22. A lidocaine drip is infusing at 30 ml/hr on an infusion device. The drug is mixed 2 g in 500 ml D5W. How many mg/minute is the patient receiving?

1. 5 mg/min
2. 4 mg/min
3. 3 mg/min
4. 2 mg/min

23. Aminophylline is infusing at 30 ml/hr. The drug is mixed 250 mg in 500 ml D5W. How many mg/hr is the patient receiving?

1. 30 mg/hr
2. 25 mg/hr
3. 20 mg/hr
4. 15 mg/hr

24. The cardiac patient is to receive Cardizem 5 mg IVP. The vial contains 10 mg/2 ml. How many ml will you give?

1. 10 ml
2. 5 ml
3. 2 ml
4. 1 ml

25. The patient is to take Aspirin gr. X. The bottle contains Aspirin 300 mg tablets. How many tablets should he take?

1. 0.5 tablet
2. 1 tablet
3. 1.5 tablets
4. 2 tablets

26. Digoxin 125 mcg is ordered IVP every a.m. The vial contains 0.5 mg in 2 ml. How many ml will you give?

1. 0.2 ml
2. 0.5 ml
3. 1.5 ml
4. 2 ml

27. The pre-op patient is ordered Atropine gr. 1/150 IM. The vial contains Atropine 0.4 mg in 1 ml. How much will you give?

1. 1 ml
2. 1.5 ml
3. 2 ml
4. 2.5 ml

28. The patient is to receive Heparin 1500 units/hr by IV infusion. The IV contains 25,000 units of Heparin in 250 ml of D5W. At what rate should you set the IV pump (ml/hr)?

1. 15 ml/hr
2. 16 ml/hr
3. 17 ml/hr
4. 20 ml/hr

29. The IV with Nitroglycerin is infusing at 6 ml/hr. The concentration of the IV is 50 mg in 250 ml of D5W. How many mg/hr is the patient receiving?

1. 1.2 mg/hr
2. 5.2 mg/hr
3. 25 mg/hr
4. 30 mg/hr

Situation: The patient is ordered an IV of 1000 ml of Normal Saline over 8 hours.

30. At what rate would you set the IV pump (ml/hr)?

1. 125 ml/hr
2. 250 ml/hr
3. 100 ml/hr
4. 2 ml/hr

31. How many drops per minute would you set the gravity IV tubing with a drip factor of 15 drops/ml?

1. 35 gtts/min
2. 19 gtts/min
3. 31 gtts/min
4. 15 gtts/min

32. If the current IV bag was started at 1:00, what time would you hang the next bag?

1. 5:00
2. 7:00
3. 9:00
4. 11:00

33. The patient with an infection is to receive an IVPB of Ampicillin 500 mg in 50 ml over 30 minutes. At what rate would you set the pump?

1. 300 ml/hr
2. 200 ml/hr
3. 100 ml/hr
4. 50 ml/hr

34. An IVPB of Vancomycin 1 gram in 250 ml is to infuse over 90 minutes. At what rate should the pump be set?

1. 28 ml/hr
2. 90 ml/hr
3. 167 ml/hr
4. 270 ml/hr

35. The patient is ordered Fortaz 250 mg IM. The vial contains 500 mg powder with directions to add 1.5 ml of sterile water for a total volume of 1.8 ml. How many ml will you administer?

1. 5 ml
2. 3.6 ml
3. 2 ml
4. 0.9 ml

36. The physician ordered an IV of Dobutamine at 5 mcg/Kg/min. The patient weighs 198 lbs. The IV solution is 500 mg Dobutamine in 250 ml D5W. How many ml/hr should the pump be set?

1. 2.5 ml/hr
2. 5 ml/hr
3. 10 ml/hr
4. 14 ml/hr

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $0.25, g= 250, mgRightarrow frac{250, mg}{125, mg}times 1, tab= 2, tabs$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $1, tsp= 5, mlRightarrow frac{8, mg}{4, mg}times 5, ml= 10, ml$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $gr, 1/10= 6, mgRightarrow frac{6, mg}{10, mg}times 1, ml= 0.6, ml$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $50, mg/kgtimes 25.5, kg= 1,275, mg$ $frac{1,275, mg}{100, mg}times 1, ml= 12.75, ml, or, 12.8, ml$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: 45 mg/kg/day x 30 kg = 1.350 mg/day ÷ 3 doses = 450 mg per dose $frac{450, mg}{125, mg}times 1, ml, div 3, doses= 3.6, ml$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
BSA Formula: $frac{child's, BSA, [m^{2}]times usual, adult dose}{1.7, m^{2}}= child's, dose$
Solution: $frac{0.55, m^{2}times 500, mg}{1.7, m^{2}}= 161.76Rightarrow frac{161.76, mg}{50, mg}times 1, ml= 3.2, ml$

BSA Formula: $frac{child's, BSA, [m^{2}]times usual, adult dose}{1.7, m^{2}}= child's, dose$
Solution: $frac{1.2, m^{2}times 25, mg}{1.7, m^{2}}= 17.6, mg$

IV Flow Formula: $frac{volume, to, be, infused, (ml)}{time, (minutes)}times calibration, (gtt/ml)= flow rate, (gtt/min)$
Solution: $frac{125, ml}{60, mins}times 15, gtt/ml= 31.25Rightarrow 31, gtt/min$

IV Flow Formula: $frac{volume, to, be, infused, (ml)}{time, (minutes)}times calibration, (gtt/ml)= flow rate, (gtt/min)$
Solution: $frac{1,000, ml}{1,440, mins}times 60, gtt/ml= 41.67Rightarrow 42, gtt/min$

10. Answer: D. 2 hrs and 30 mins

Solution: 200 ÷ 80 = 2.5 = 2 hrs and 30 mins

IV Flow Formula: $frac{volume, to, be, infused, (ml)}{time, (minutes)}times calibration, (gtt/ml)= flow rate, (gtt/min)$
Solution: $frac{100, ml}{20, mins}times 15, gtt/ml= 75, gtt/min$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $frac{900, units/hr}{10,000, units}times 500, ml= 45, ml/hr$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $frac{1,000, units/hr}{40,000, units}times 1,000, ml= 25, ml/hr$

Solution: $frac{20,000, units}{500, ml}= frac{x, units}{28, ml/hr} Rightarrow 1,120, units/hr$

Solution: $frac{25,000, units}{250, ml}= frac{x, units}{11, ml/hr} Rightarrow 1,100, units/hr$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $frac{20, units/hr}{100, units}times 250, ml= 50, ml/hr$

Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $frac{40, mg/hr}{500, mg}times 250, ml= 20, ml/hr$

1. Infusion device is set at hourly rate, so convert mcg/min to mcg/hr
15 mcg/min = 900 mcg/hr (15 x 60)

2. Drug is expressed in mg, so covert mcg to mg
900 mcg/hr = 0.9 mg/hr

3. Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $frac{0.9, mg/hr}{50, mg}times 500, ml= 9, ml/hr$

1. Convert lbs to kg
168 ÷ 2.2 = 76.36 = 76.4 kg

2. Calculate the minute rate
76.4 kg x 10 mcg/kg/min = 764 mcg/min

3. Calculate hourly rate
764 mcg/min x 60 mins/hr = 45,840 mcg/hr

4. Drug is expressed in mg, so convert mcg to mg
45,840 mcg = 45.84 mg

5. Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $frac{45.84, mg}{250, mg}times 250, ml= 46, ml/hr$

1. Convert lbs to kg
205 ÷ 2.2 = 93.18 = 93.2 kg

2. Calculate the minute rate
93.2 kg x 5 mcg/kg/min = 466 mcg/min

3. Calculate hourly rate
466 mcg/min x 60 mins/hr = 27,960 mcg/hr

4. Drug is expressed in mg, so convert mcg to mg
27,960 mcg = 27.96 mg

5. Formula: $frac{desired, amount}{have, on, hand}times quantity= x$
Solution: $frac{27.96, mg}{200, mg}times 250, ml= 35, ml/hr$

1. Convert 50 mg to mcg = 50,000 mcg

2. Use ratio/proportion to solve $frac{50,000, mcg}{500, ml}= frac{x, mcg}{15, ml/hr}$
x = 1,500 mcg/hr

3. Calculate the minute rate
1,500 mcg/hr ÷ 60 mins/hr = 25 mcg/min

1. Convert 2 g to mg = 2,000 mg

2. Use ratio/proportion to solve $frac{2,000, mg}{500, ml}= frac{x, mg}{30, ml/hr}$
x = 120 mg/hr

3. Calculate the minute rate
120 mg/hr ÷ 60 mins/hr = 2 mg/min $hugefrac{250, mg}{500, ml}= frac{x, mg}{30, ml/hr}$
x = 15 mg/hr

10 mg : 2 ml = 5 mg : x ml
10 x = 10
x = 1

1 grain = 60 mg
10 grains = 600 mg
300 mg : 1 tab = 600 mg: x tabs

1 mg = 1000 mcg
0.5 mg : 2 ml = .125 mg : x ml

1gr = 60 mg
1/150 gr – .4 mg
0.4 mg : 1 ml = 0.4 mg : x ml

25,000 units : 250 ml = 1,500 units : x ml
*Remember a pump setting is always ml/hour

50 mg : 250 ml = x mg : 6 ml

1,000 ml ÷ 8 hrs

125 ml ÷ 60 min x 15 gtts/ml

50 ml : 30 min = x ml : 60 min

250 ml : 90 min = x ml : 60 min