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hydroxyzine Nursing Considerations & Management

Drug Name
Generic Name :hydroxyzine , hydroxyzine hydrochloride , hydroxyzine pamoate Brand Name:
  • Oral preparations: Apo-Hydroxyzine (CAN), Novo-Hydroxyzine (CAN), Vistaril
  • Parenteral preparations: Vistaril
  • Oral preparations: Vistaril
Classification: Anxiolytic, Antihistamine, Antiemetic Pregnancy Category C
Dosage & Route
Available forms : Tablets—10, 25, 50, 100 mg; syrup—10 mg/5 mL; capsules—25, 50, 100 mg; vocal suspension—25 mg/5 mL; introduction—25, 50 mg/mL Dosages : Start patients on IM therapy when indicated; use vocal therapy for livelihood. Adjust dosage to patient’s reply.
  • Symptomatic assistance of regard: 50–100 mg qid.
  • Management of pruritus: 25 mg tid–qid.
  • Sedative (preoperative and postoperative): 50–100 mg.
  • Psychiatric and moving emergencies, including alcoholism: 50–100 mg straightway and q 4–6 hr as needed.
  • Nausea and vomiting: 25–100 mg.
  • Preoperative and postoperative, prepartum and postpartum: 25–100 mg.
  • Anxiety, pruritus:
    • < 6 yr: 50 mg/day in divided doses.
    • > 6 yr: 50–100 mg/day in divided doses.
  • Sedative: 0.6 mg/kg.
  • Nausea, preoperative and postoperative: 1.1 mg/kg (0.5 mg/lb).
Therapeutic actions
  • Hydroxyzine blocks histamine H1-receptors on effector cells of the GI hope, dignity vessels and respiratory hope; a sedating anihistamine after a while antimuscarinic and speaking soothing properties. It to-boot possesses skeletal muscle relaxing, bronchodilator, antiemetic and analgesic properties.
  • Symptomatic assistance of regard and strain associated after a while psychoneurosis; supplement in radical distemper states in which regard is manifested; alcoholism and asthma; anteriorly dental procedures
  • Management of pruritus due to allergic provisions, such as constant urticaria, atopic and contiguity dermatosis, and in histamine-mediated pruritus
  • Sedation when used as premedication and forthcoming unconcealed anesthesia
  • Control of qualm and vomiting and as supplement to analgesia preoperatively and postoperatively (parenteral) to tolerate decreased opioid dosage
  • IM administration: Management of the sharply uneasy or hysterical patient; the sharp or constant alcoholic after a while regard after a whiledrawal symptoms or hallucination tremens; as preoperative and postoperative and prepartum and postpartum supplementive medication to encourage diminution in opioid dosage, tranquilize regard, and moderate emesis
Adverse effects
  • CNS dejection, absurd CNS stimulation, dry opening, thickened respiratory secretions, constipation, blurring of desire, tachycardia, GI disturbances, dissipation, hypotension, tinnitus.
  • Porphyria, neonates, pregnancy, lactation.
Nursing considerations
  • History: Allergy to hydroxyzine or cetirizine, uncomplicated vomiting in upshot, lactation, pregnancy
  • Physical: Skin pretense, lesions, texture; orientation, reflexes, affect; R, unsupposable sounds
  • WARNING: Determine and speak underlying object of vomiting. Offal may mask signs and symptoms of regardful provisions, such as brain tooth, intestinal hinderance, or appendicitis.
  • Do not carry parenteral disintegration subcutaneously, IV, or intra-arterially; construction necrosis has occurred after a while subcutaneous and intra-arterial introduction, and hemolysis after a while IV introduction.
  • Give IM introductions penetrating into a liberal muscle: In adults, use excellent outward quadrant of buttocks or midlateral thigh; in upshot use midlateral thigh muscles; use deltoid area solely if polite open.
Teaching points
  • Take this offal as prescribed. Dodge exorbitant dosage.
  • You may proof these laterality effects: Dizziness, sedation, swoon (use timidity if driving or performing tasks that exact cheerfulness); dodge alcohol, soothings, doze aids (careful overdosage could end); dry opening (numerous opening regard, sucking on sugarless lozenges may acceleration).
  • Report inaptitude active, tremors, dropping of coordination, shrewd muscles, or muscle spasms.


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