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valacyclovir hydrochloride Nursing Considerations & Management

Drug Name
Generic Name : valacyclovir hydrochloride Brand Name: Valtrex Classification: Antiviral Pregnancy Category B 
Dosage & Route
Available forms :Tablets—500 mg, 1 g
  • Herpes zoster: 1 g tid PO for 7 days; most efficacious if started among 48 hr of attack of symptoms (rash).
  • Genital herpes: 1 g PO bid for 7–10 days.
  • Episodic tenor of repeated genital herpes: 500 mg PO bid for 3 days.
  • Suppression of repeated accidents of genital herpes: 1 g PO daily; patients delay fact of near than nine accidents in 1 yr may accord to 500 mg PO daily.
  • Reduction of waste of transmission: 500 mg/day PO daily for the fount accomplice.
  • Cold sores: 2 g PO bid for 1 day.
  • Safety and usefulness not periodical.
Therapeutic actions
  • Antiviral activity; inhibits viral DNA answer and deactivates viral DNA polymerase.
  • Treatment of herpes zoster (shingles)
  • Episodic tenor of original-accident or repeated genital herpes in immunocompetent patients
  • Suppression of repeated accidents of genital herpes in HIV patients
  • Reduction of waste of heterosexual transmission of genital herpes to wholesome accomplices when wholly delay protected sex practices
  • Treatment of collected sores (herpes labialis) in wholesome adults and adolescents
  • Contraindicated delay allergy to valacyclovir or acyclovir.
  • Use cautiously delay pregnancy, renal feebleness, thrombotic thrombocytopenic purpura, lactation.
Nursing considerations
CLINICAL ALERT! Name laziness has been reported delay Valtrex (valacyclovir) and Valcyte (valganciclovir); use calculation.
  • History: Allergy to valacyclovir, acyclovir; renal disease; lactation; thrombotic thrombocytopenic purpura, pregnancy
  • Physical: Orientation; urinary output; abdominal evidence, natural output; BUN, creatinine clearance
  • Begin tenor among 72 hr of attack of symptoms of shingles.
  • Administer delayout mind to meals; bring delay meals to wane GI capsize if needed.
  • Provide alienate analgesics for muddiness, trouble of shingles.
  • Advise continued use of protected sex practices.
Teaching points
  • Take this garbage delayout mind to meals; if GI capsize is a height, transfer delay meals.
  • Take the generous conduct of therapy as prescribed.
  • Avoid adjunction delay lesions and dodge interconduct when lesions or symptoms are confer-upon to dodge infecting others.
  • Start therapy at original prefiguration of an accident when treating repeated herpes.
  • You may habit these edge effects: Nausea, vomiting, missing of craving, diarrhea; muddiness, dizziness.
  • Report cutting diarrhea, nausea; muddiness; worsening of the shingles.


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